HYAL3 / Unconjugated /
HYAL3 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb11658-100ug (View supplier product page) | |
| Size | 100 μg | |
| Price | $553.00 | |
| Antigen | HYAL3 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse | |
| Applications | WB, IHC-P | |
| Description | Rabbit polyclonal antibody to HYAL3 (hyaluronoglucosaminidase 3) which is also known as LUCA3; HYAL-3; LUCA-3. It belongs to the hyaluronidase family and they play role in cell proliferation, migration, differentiation and sperm function. It expressed in bone marrow, testis and kidney, but has relatively low expression in all other tissues. HYAL3 is an unlikely tumor supressor candidate, given the lack of detected mutations in its gene. |
About HYAL3 and Purified
| HYAL3 | This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011] |
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Images
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Western blot analysis of 22RV Cell Lysate (Lane1), HELA Cell Lysate (Lane2) and V20S Cell Lysate (Lane3) using HYAL3 antibody, Immunohistochemical analysis of formalin-fixed and paraffin embedded Human mammary cancer tissue using HYAL3 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$553.00
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