HIRA / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb447429-100ug (View supplier product page)
Size 100 μg
Price $451.00
Antigen HIRA
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse, Rat
Applications WB, IHC-P, ELISA
Description Rabbit polyclonal antibody against HIRA conjugated to Biotin
About HIRA and Biotin
HIRA This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
Citations
Additional
Sources
Reviews & Ratings
Biotin Excitation and Emission Spectra