HDAC5 / Unconjugated /
HDAC5 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb214953-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $258.40 | |
| Antigen | HDAC5 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB, IHC-P, IF, ICC, IP | |
| Description | Rabbit polyclonal antibody to HDAC5 |
About HDAC5 and Purified
| HDAC5 | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
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Images
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Western blot analysis of MCF7 (Lane 1), HeLa (Lane 2), NIH3T3 (Lane 3), H9C2 (Lane 4) whole cell lysates using HDAC5 antibody, Immunohistochemical analysis of formalin-fixed and paraffin-embedded human breast cancer tissue using HDAC5 antibody (dilution at 1:200), Immunofluorescense analysis of HeLa cells lysates using HDAC5 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$258.40
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