GSTM1 / Unconjugated /
GSTM1 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb506868-400ul (View supplier product page) | |
| Size | 400 μl | |
| Price | $383.00 | |
| Antigen | GSTM1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, IHC-P, FC | |
| Description | Rabbit polyclonal antibody to GSTM1 |
About GSTM1 and Purified
| GSTM1 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
|---|
Images
|
Flow cytometric analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram) using GSTM1 antibody, Immunohistochemical staining of paraffin embedded human hepatocarcinoma tissue using GSTM1 antibody, Western blot analysis of huamn liver tissue, Jurkat cell line (from left to right) using GSTM1 antibody |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Purified Excitation and Emission Spectra
$383.00
Supplier Page
Supplier Page
