GSTM1 / Unconjugated / 1H4F2
GSTM1 / Unconjugated / 1H4F2
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb97401-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $374.00 | |
| Antigen | GSTM1 | |
| Clone | 1H4F2 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | Unconjugated | |
| Target Species | Human, Rat | |
| Applications | ELISA, WB, IHC-P, FC | |
| Description | Mouse monoclonal antibody to GSTM1 |
About GSTM1 and Purified
| GSTM1 | Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008] |
|---|
Images
|
Line graph illustrates about the Ag-Ab reactions using different concentrations of antigen and serial dilutions of GSTM1 antibody, Flow cytometric analysis of Hela cells using GSTM1 antibody, IHC-P of esophageal cancer tissues using GSTM1 antibody, Western blot analysis of MCF-7 (Lane1), PC-12 (Lane2), Jurkat (Lane3), Hela (Lane4), HL7702 (Lane5) and HepG2 (Lane6) cell lysate using GSTM1 antibody, Immunohistochemical analysis of formalin fixed and paraffin-embedded stomach cancer tissues using GSTM1 antibody, Western blot analysis of human GSTM1 (AA: 23-181) recombinant protein using GSTM1 antibody |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Purified Excitation and Emission Spectra
$374.00
Supplier Page
Supplier Page
