FMO5 / Unconjugated /
FMO5 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb137911-100ug (View supplier product page) | |
| Size | 100 μg | |
| Price | $476.00 | |
| Antigen | FMO5 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human, Mouse, Rat | |
| Applications | WB | |
| Description | Rabbit polyclonal to FMO5. Dimethylaniline monooxygenase [N-oxide-forming] 5 also known as FMO 5 is an enzyme that in humans is encoded by the FMO5 gene. By fluorescence in situ hybridization, this gene was assigned to human chromosome 1q21.1. FMO5 is not an efficient drug-metabolizing enzyme and that it may have an alternative physiologic role. FMO5 transcripts play an important role in progesterone-regulated in breast cancer cells specifically under the control of the progesterone receptor B-isoform. |
About FMO5 and Purified
| FMO5 | Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2009] |
|---|
Images
|
Western blot analysis of Lane 1: Mouse Liver Tissue Lysate, Lane 2: Mouse Testis Tissue Lysate, Lane 3: Mouse Spleen Tissue Lysate using FMO5 antibody |
Citations
| Additional Sources |
|
|---|
Reviews & Ratings
Purified Excitation and Emission Spectra
$476.00
Supplier Page
Supplier Page
