FBXL4 / Unconjugated /

Product Details
Supplier Biorbyt
Catalog #: orb137989-100ug (View supplier product page)
Size 100 μg
Price $553.00
Antigen FBXL4
Clone
Host Rabbit
Isotype IgG
Conjugate Unconjugated
Target Species Human, Mouse, Rat
Applications WB, IHC-P
Description Rabbit polyclonal to FBXL4. FBXL4, also known as FBL4 or FBL5 encodes a member of the F-box protein family, which is characterized by an approximately 40 amino acid motif, the F-box. This gene is mapped to 6q16.1. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A.
About FBXL4 and Purified
FBXL4 This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Images
  FBXL4 Purified Biorbyt antibody anti target:Human, Mouse, Rat host:Rabbit isotype:IgG clone: Western blot analysis of Lane 1: Rat Liver Tissue Lysate, Lane 2: Rat Lung Tissue Lysate, Lane 3:...

Western blot analysis of Lane 1: Rat Liver Tissue Lysate, Lane 2: Rat Lung Tissue Lysate, Lane 3: HELA Cell Lysate, Lane 4: PANC Cell Lysate using FBXL4 antibody, Immunohistochemical analysis of formalin-fixed paraffin embedded Human Lung Cancer Tissue using FBXL4 antibody

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Purified Excitation and Emission Spectra