EP300 / Unconjugated /
EP300 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb213896-200ul (View supplier product page) | |
| Size | 200 μl | |
| Price | $404.60 | |
| Antigen | EP300 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Canine, Human, Mouse, Rat | |
| Applications | WB, IHC-P | |
| Description | Rabbit polyclonal antibody to EP300 |
About EP300 and Purified
| EP300 | This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008] |
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Images
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Western blot analysis of A431 (Lane 1), HeLa (Lane 2), HT29 (Lane 3), A549 (Lane 4), NIH3T3 (Lane 5), PC12 (Lane 6) whole cell lysates using EP300 antibody, Immunohistochemical analysis of formalin-fixed and paraffin-embedded human lung cancer tissue using EP300 antibody (dilution at 1:200) |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$404.60
Supplier Page
Supplier Page
