FluoroFinder

	Supplier	Biorbyt
	Catalog #:	orb248953-200ul (View supplier product page)
	Size	200 μl
	Price	$501.50
	Antigen	CD86
	Clone	CN5E1
	Host	Mouse
	Isotype	IgG1
	Conjugate	Unconjugated
	Target Species	Human
	Applications	IF, ICC, FC
	Description	Mouse monoclonal antibody to CD86

	CD86	This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011]