APE1 / Unconjugated /
APE1 / Unconjugated /
Product Details
| Supplier | Biorbyt | |
|---|---|---|
| Catalog #: | orb74014-100ul (View supplier product page) | |
| Size | 100 μl | |
| Price | $589.00 | |
| Antigen | APE1 | |
| Clone | ||
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | Unconjugated | |
| Target Species | Human | |
| Applications | WB, IF, ICC | |
| Description | Rabbit polyclonal to APE1. |
About APE1 and Purified
| APE1 | The APEX gene encodes the major AP endonuclease in human cells. It encodes the APEX endonuclease, a DNA repair enzyme with apurinic/apyrimidinic (AP) activity. Such AP activity sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. The AP sites are the most frequent pre-mutagenic lesions that can prevent normal DNA replication. Splice variants have been found for this gene; all encode the same protein. Disruptions in the biological functions related to APEX are associated with many various malignancies and neurodegenerative diseases.[provided by RefSeq, Dec 2019] |
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Images
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Western Blot analysis of A:A549 whole cell lysate using APE1 antibody, Confocal immunofluorescence analysis of paraformaldehyde-fixed A431 using APE1 antibody |
Citations
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Reviews & Ratings
Purified Excitation and Emission Spectra
$589.00
Supplier Page
Supplier Page
