Protein Disulfide Isomerase / Biotin /

Product Details
Supplier Biorbyt
Catalog #: orb447878-100ug (View supplier product page)
Size 100 μg
Price $451.00
Antigen Protein Disulfide Isomerase
Clone
Host Rabbit
Isotype IgG
Conjugate Biotin
Target Species Human, Mouse, Rat
Applications WB, IHC-P, ELISA
Description Rabbit polyclonal antibody against PDI conjugated to Biotin
About Protein Disulfide Isomerase and Biotin
Protein Disulfide Isomerase This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
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Biotin Excitation and Emission Spectra