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Alexa Fluor 680

Alexa Fluor™ 680 (Ex-Max 679 nm/Em-Max 702 nm)

Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy.

Excitation & emission spectra

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Key facts

Excitation maximum
679 nm
Emission maximum
702 nm
Optimal laser line
628-640
Optimal filter
695/40
Relative brightness
1 of 5
Extinction coefficient
184000
Quantum yield
0.36
Commercial antibodies
6.9k from 8 suppliers

Alexa Fluor 680 has an excitation maximum at 679 nm and an emission maximum at 702 nm, a Stokes shift of 23 nm. Its extinction coefficient is 184000 M⁻¹cm⁻¹. It is optimally excited by the 628-640 laser line.

Frequently asked questions

What is Alexa Fluor 680?
Alexa Fluor™ 680 (AF680, Alexa 680) has an excitation peak at 679 nm and an emission peak at 702 nm, and is spectrally similar to Cy®5.5 (GE Healthcare), IR680® (Licor), iFluor® 680 (ATT Bioquest) and iFluor® 700 (ATT Bioquest). Alexa 680 is commonly used for flow cytometry, fluorescence microscopy and super-resolution microscopy.
What laser excites Alexa Fluor 680?
Alexa Fluor 680 is optimally excited by the 628-640 laser line. Its excitation maximum is 679 nm.
What filter should I use to detect Alexa Fluor 680?
A 695/40 filter captures the peak of the Alexa Fluor 680 emission near 702 nm with minimal spillover.
How bright is Alexa Fluor 680?
Alexa Fluor 680 has a relative brightness of 1 out of 5 (quantum yield 0.36).
How many antibodies are available conjugated to Alexa Fluor 680?
FluoroFinder tracks 6898 commercially available Alexa Fluor 680 conjugates, searchable by target, clone, host and application.