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Protoporphyrin IX

Protoporphyrin IX (Ex-Max 393 nm/Em-Max 621 nm)

Protoporphyrin IX is a naturally occurring autofluorescent compound involved in heme biosynthesis. It's tetrapyrrole structure enables it to chelate transitional metals. Specifically, chelation of PPIX with iron forms heme.

Excitation & emission spectra

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Key facts

Excitation maximum
393 nm
Emission maximum
621 nm
Optimal laser line
405
Optimal filter
610/20
Relative brightness
1 of 5
Commercial antibodies
1 from 1 supplier

Protoporphyrin IX has an excitation maximum at 393 nm and an emission maximum at 621 nm, a Stokes shift of 228 nm. It is optimally excited by the 405 laser line.

Frequently asked questions

What is Protoporphyrin IX?
Protoporphyrin IX is a naturally occurring autofluorescent compound involved in heme biosynthesis. It's tetrapyrrole structure enables it to chelate transitional metals. Specifically, chelation of PPIX with iron forms heme.
What laser excites Protoporphyrin IX?
Protoporphyrin IX is optimally excited by the 405 laser line. Its excitation maximum is 393 nm.
What filter should I use to detect Protoporphyrin IX?
A 610/20 filter captures the peak of the Protoporphyrin IX emission near 621 nm with minimal spillover.
How bright is Protoporphyrin IX?
Protoporphyrin IX has a relative brightness of 1 out of 5.
How many antibodies are available conjugated to Protoporphyrin IX?
FluoroFinder tracks 1 commercially available Protoporphyrin IX conjugates, searchable by target, clone, host and application.