MSH2

Aliases: COCA1, FCC1, HNPCC, HNPCC1, LCFS2, MMRCS2, MSH-2, hMSH2
Other: DNA mismatch repair protein Msh2|DNA mismatch repair protein Msh2 transcript|MutS-like 2|mutS homolog 2, colon cancer, nonpolyposis type 1

This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Agarose


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NB600-424
IP MSH2
Human
Rabbit
IgG
100 μg
$429
Details 
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