cleaved Retinoblastoma 1
| Aliases: | OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110 |
|---|---|
| Other: | retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more
Janelia Fluor 549
| Common Laser: | 532 |
|---|---|
| Common Filter: | 586/25 |
| Excitation Peak: | 549 |
| Emission Peak: | 571 |
Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP... see more
Popular cleaved Retinoblastoma 1 Janelia Fluor 549 Antibodies
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