cleaved Retinoblastoma 1
| Aliases: | OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110 |
|---|---|
| Other: | retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein |
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more
DyLight 755
| Common Laser: | 730-750 |
|---|---|
| Common Filter: | 780/60 |
| Excitation Peak: | 754 |
| Emission Peak: | 776 |
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
Popular cleaved Retinoblastoma 1 DyLight 755 Antibodies
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