cleaved Retinoblastoma 1

Aliases: OSRC, PPP1R130, RB, p105-Rb, p110-RB1, pRb, pp110
Other: retinoblastoma-associated protein|GOS563 exon 17 substitution mutation causes premature stop|exon 17 tumor GOS561 substitution mutation causes premature stop|prepro-retinoblastoma-associated protein|protein phosphatase 1, regulatory subunit 130|retinoblastoma 1|retinoblastoma suspectibility protein

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder... see more

DyLight 405LS


Popular cleaved Retinoblastoma 1 DyLight 405LS Antibodies


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NB100-56598V3
WB,IHC-Fr,IHC-P cleaved Retinoblastoma 1
Human,Mouse
Mouse
IgG1
172C1094
100 μl
$329
Details 
 Browse cleaved Retinoblastoma 1 / DyLight 405LS antibodies.