Bcl-2

Aliases: Bcl-2, PPP1R50
Other: apoptosis regulator Bcl-2|B-cell CLL/lymphoma 2|protein phosphatase 1, regulatory subunit 50

This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

V450

Common Laser: 405
Common Filter: 450/40
Excitation Peak: 404
Emission Peak: 448

V450 (Horizon V450) from BD Biosciences has an excitation peak at 406 nm and an emission peak at 450 nm. It is spectrally similar to eFluor™ 450 (ThermoFisher Scientific), Vio®Blue® (Miltenyi Biotec), Alexa Fluor™ 405 (ThermoFisher Scientific), Cascade Blue® (ThermoFisher Scientific), Pacific Blue (ThermoFisher Scientific), and ATTO 425 (ATTO-Tec)


Popular Bcl-2 V450 Antibodies


Company /
SKU
Applications Marker /
Reactivity
Host / Isotype /
Clone
Size /
Price
Details
BD Biosciences
560637
FC Bcl-2
Human
Mouse
IgG1 κ
Bcl-2/100
50 Tests
$294
Details 
 Browse Bcl-2 / V450 antibodies.