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Hoechst (33258)

Hoechst (33258) (Ex-Max 352 nm/Em-Max 454 nm)

Hoechst (33258) is a cell-permeant, fluorogenic nucleic acid stain. It has an excitation peak at 352 nm and an emission peak at 454 nm. It is useful in counter-staining nuclei in both flow cytometry and microscopy.

Excitation & emission spectra

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Key facts

Excitation maximum
352 nm
Emission maximum
454 nm
Optimal laser line
355
Optimal filter
450/50
Extinction coefficient
46000
Commercial antibodies
4 from 2 suppliers

Hoechst (33258) has an excitation maximum at 352 nm and an emission maximum at 454 nm, a Stokes shift of 102 nm. Its extinction coefficient is 46000 M⁻¹cm⁻¹. It is optimally excited by the 355 laser line.

Frequently asked questions

What is Hoechst (33258)?
Hoechst (33258) is a cell-permeant, fluorogenic nucleic acid stain. It has an excitation peak at 352 nm and an emission peak at 454 nm. It is useful in counter-staining nuclei in both flow cytometry and microscopy.
What laser excites Hoechst (33258)?
Hoechst (33258) is optimally excited by the 355 laser line. Its excitation maximum is 352 nm.
What filter should I use to detect Hoechst (33258)?
A 450/50 filter captures the peak of the Hoechst (33258) emission near 454 nm with minimal spillover.
How many antibodies are available conjugated to Hoechst (33258)?
FluoroFinder tracks 4 commercially available Hoechst (33258) conjugates, searchable by target, clone, host and application.