Loading the Dye Directory…

DiO

DiO (Ex-Max 487 nm/Em-Max 504 nm)

DiO is a lipophilic carbocyanine dye often used in fluorescence microscopy to label the cell surface, trace neuronal axons or, upon fixation, any lipid bound compartment. This probe has an excitation peak at 487 nm and an emission peak at 504 nm

Excitation & emission spectra

400450500550600650700750800

Key facts

Excitation maximum
487 nm
Emission maximum
504 nm
Optimal laser line
488
Optimal filter
515/30
Molecular weight
881.7173
Commercial antibodies
6 from 2 suppliers

DiO has an excitation maximum at 487 nm and an emission maximum at 504 nm, a Stokes shift of 17 nm. It is optimally excited by the 488 laser line.

Frequently asked questions

What is DiO?
DiO is a lipophilic carbocyanine dye often used in fluorescence microscopy to label the cell surface, trace neuronal axons or, upon fixation, any lipid bound compartment. This probe has an excitation peak at 487 nm and an emission peak at 504 nm
What laser excites DiO?
DiO is optimally excited by the 488 laser line. Its excitation maximum is 487 nm.
What filter should I use to detect DiO?
A 515/30 filter captures the peak of the DiO emission near 504 nm with minimal spillover.
How many antibodies are available conjugated to DiO?
FluoroFinder tracks 6 commercially available DiO conjugates, searchable by target, clone, host and application.